11428 E Artesia Blvd, Suite 28
Artesia, California

Ghassan Gholmieh MD, PhD

      Dr Gholmieh Testimony - Gholmieh



The name Episolve GI is a combination of Epig + solve + GI. Epig represents epigastric pain which is one of the medical terminologies for heartburn. Episolve GI “solves” the epigastric pain and supports the gastrointestinal (GI) system. Episolve GI was created by Ghassan Gholmieh, MD, PhD



Ghassan Gholmieh finished his residency in Internal Medicine at USC County Hospital in 2005. Dr Gholmieh also graduated with a Masters in Biomedical Imaging  in 2001 and a PhD in Biomedical Engineering in December 2002 with an emphasis on Neural Engineering.  Ghassan is a former assistant professor of research at USC. Ghassan has pursued startup ventures in the bioengineering field.  He founded MultiMicroElectrode Systems in 2004.

Publications Authored (partial list):

Modeling the nonlinear properties of the in vitro hippocampal perforant path-dentate system using multielectrode array technology.Dimoka A, Courellis SH, Gholmieh GI, Marmarelis VZ, Berger TW.IEEE Trans Biomed Eng. 2008 Feb;55(2 Pt 1):693-702. doi: 10.1109/TBME.2007.908075.

 Spontaneous stellate ganglion nerve activity and ventricular arrhythmia in a canine model of sudden death.Zhou S, Jung BC, Tan AY, Trang VQ, Gholmieh G, Han SW, Lin SF, Fishbein MC, Chen PS, Chen LS. Heart Rhythm. 2008 Jan;5(1):131-9. Epub 2007 Sep 16.

Improving bioassay sensitivity for neurotoxins detection using volterra based third order nonlinear analysis.Gholmieh GI, Courellis SH, Fluster D, Chen LS, Marmarelis VZ, Baudry M, Berger TW.Conf Proc IEEE Eng Med Biol Soc. 2007;2007:2261-4.

Screening for the effects of antiepileptic drugs on short term plasticity using a time efficient bioassay.Gholmieh GI, Courellis SH, Chen LS. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:2247-52.

VLSI implementation of a nonlinear neuronal model: a “neural prosthesis” to restore hippocampal trisynaptic dynamics.Hsiao MC, Chan CH, Srinivasan V, Ahuja A, Erinjippurath G, Zanos TP, Gholmieh G, Song D, Wills JD, LaCoss J, Courellis S, Tanguay AR Jr, Granacki JJ, Marmarelis VZ, Berger TW.Conf Proc IEEE Eng Med Biol Soc. 2006;1:4396-9.

Left stellate ganglion and vagal nerve activity and cardiac arrhythmias in ambulatory dogs with pacing-induced congestive heart failure.Ogawa M, Zhou S, Tan AY, Song J, Gholmieh G, Fishbein MC, Luo H, Siegel RJ, Karagueuzian HS, Chen LS, Lin SF, Chen PS. J Am Coll Cardiol. 2007 Jul 24;50(4):335-43. Epub 2007 Jul 10.

Nonlinear dynamic model of CA1 short-term plasticity using random impulse train stimulation. Gholmieh G, Courellis S, Marmarelis V, Berger T. Ann Biomed Eng. 2007 May;35(5):847-57. Epub 2007 Mar 23.

Circadian variations of stellate ganglion nerve activity in ambulatory dogs. Jung BC, Dave AS, Tan AY, Gholmieh G, Zhou S, Wang DC, Akingba AG, Fishbein GA, Montemagno C, Lin SF, Chen LS, Chen PS. Heart Rhythm. 2006 Jan;3(1):78-85.

Custom-designed high-density conformal planar multielectrode arrays for brain slice electrophysiology. Gholmieh G, Soussou W, Han M, Ahuja A, Hsiao MC, Song D, Tanguay AR Jr, Berger TW. J Neurosci Methods. 2006 Apr 15;152(1-2):116-29. Epub 2005 Nov 9.

Restoring lost cognitive function.Berger TW, Ahuja A, Courellis SH, Deadwyler SA, Erinjippurath G, Gerhardt GA, Gholmieh G, Granacki JJ, Hampson R, Hsaio MC, LaCoss J, Marmarelis VZ, Nasiatka P, Srinivasan V, Song D, Tanguay AR, Wills J. IEEE Eng Med Biol Mag. 2005 Sep-Oct;24(5):30-44.

An algorithm for real-time extraction of population EPSP and population spike amplitudes from hippocampal field potential recordings.Gholmieh G, Courellis S, Dimoka A, Wills JD, LaCoss J, Granacki JJ, Marmarelis V, Berger T.J Neurosci Methods. 2004 Jul 30;136(2):111-21.

Detection and classification of neurotoxins using a novel short-term plasticity quantification method. Gholmieh G, Courellis S, Fakheri S, Cheung E, Marmarelis V, Baudry M, Berger T. Biosens Bioelectron. 2003 Oct 15;18(12):1467-78.

An efficient method for studying short-term plasticity with random impulse train stimuli. Gholmieh G, Courellis S, Marmarelis V, Berger T. J Neurosci Methods. 2002 Dec 15;121(2):111-27.