An Evidence-Based Approach to the Treatment of Gastroesophageal Reflux Disease.
JAMA Surg. 2016 Jan 1;151(1):73-8. doi: 10.1001/jamasurg.2015.4233. An Evidence-Based Approach to the Treatment of Gastroesophageal Reflux Disease. Patti MG1. IMPORTANCE: Gastroesophageal reflux disease (GERD) is prevalent worldwide, particularly in developed countries. It is estimated that the prevalence of GERD in the United States is approximately 20% and that it is increasing because of the epidemic of obesity. OBJECTIVE: To review the pathophysiology, clinical presentation, diagnostic evaluation, and treatment of GERD. EVIDENCE REVIEW: A search of PubMed was conducted for the years spanning 1985 to 2015 and included the following terms: heartburn, regurgitation, dysphagia, gastroesophageal reflux disease, cough, aspiration, laryngitis, GERD,...
